Isotopically Labeled Compounds
Apexbio Technology LLC AMANTADINE-D6-5MG
Amantadine-d6 (CAS No 1219805-53-4) is a deuterated form of amantadine commonly used in biomedical research It belongs to the class of adamantane derivatives and is primarily utilized as a tool compound for studying dopaminergic mechanisms and NMDA receptor pathways This compound demonstrates in vitro activity typically in the nanomolar to low micromolar range It is frequently employed in cell models and animal studies for drug screening and mechanistic investigations related to neurological disorders Amantadine-d6 provides insights into viral infections particularly those caused by influenza A viruses It is widely used to investigate resistance mechanisms and drug interactions Experimental concentrations typically depend on the specific research design This compound facilitates the understanding of pharmacokinetics and metabolic pathways through isotopic labeling helping researchers discern subtle biological processes
Apexbio Technology LLC RIFAXIMIN-D6-1MG
Rifaximin-d6 (CAS No 1262992-43-7) is a deuterated antibiotic primarily utilized in gastrointestinal research Originating as a semi-synthetic derivative of rifamycin it targets bacterial RNA synthesis by binding to the beta subunit of DNA-dependent RNA polymerase thereby inhibiting bacterial growth Demonstrating in vitro activity in the nanomolar to low micromolar range Rifaximin-d6 is commonly employed in investigations involving bacterial infections particularly in cell models and animal studies focused on the gut microbiome It is also involved in drug screening processes to evaluate antibacterial efficacy Experimental concentrations typically depend on the specific research design
Apexbio Technology LLC RIBOCICLIB-D6-1MG
Ribociclib-d6 (CAS No 1328934-40-2) is a deuterium-labeled analog of Ribociclib categorized under cyclin-dependent kinase inhibitors used in cancer research It originates from medicinal chemistry focused on enhancing pharmacokinetic properties This compound selectively inhibits CDK4 and CDK6 thereby blocking the phosphorylation of the retinoblastoma protein which leads to cell cycle arrest in the G1 phase In vitro Ribociclib-d6 demonstrates activity in the nanomolar to low micromolar range making it a valuable tool for studying the inhibition of cancer cell proliferation It is commonly used in various experimental frameworks including cell models and animal studies to evaluate its efficacy and mechanism Furthermore it plays a significant role in drug screening processes for developing targeted cancer therapies Experimental concentrations typically depend on the specific research design ensuring adaptability to diverse experimental setups
Cambridge Isotope Laboratories Dimethyl Sulfoxide-D6 (D, 99.9%) +0.03% V/V Tms, 10 G, 2206-27-1
Dimethyl Sulfoxide-D6 (D, 99.9%) +0.03% V/V Tms, 10 G, 2206-27-1
Cambridge Isotope Laboratories ISOPROPANOL-D8 (D, 99%), 25 G, 22739-76-0
ISOPROPANOL-D8 (D, 99%), 25 G, 22739-76-0
Cambridge Isotope Laboratories SODIUM DODECYL SULFATE (D25, 98%), 1 G
SODIUM DODECYL SULFATE (D25, 98%), 1 G
Cambridge Isotope Laboratories MYRISTIC ACID, SODIUM SALT (1,2,3-13C3, 99%), 0.5 G
MYRISTIC ACID, SODIUM SALT (1,2,3-13C3, 99%), 0.5 G
BIOHIPPO Anti-Phospho-SGK1 (pS422) Antibody (P10.D6), 100 µg
Phospho-SGK1 (P10.D6) Recombinant Antibody (clone pS422) is a recombinant Mouse IgG2a, kappa antibody specific for Phospho-SGK1 (P10.D6). It reacts with Human. Suitable for IHC, IP, WB. Recombinant production ensures high specificity and lot-to-lot reproducibility. Supplied as 100 ug.